A short list of reliable, free external resources for learning more about cell signaling. autocrine.com is not affiliated with any of these organisations.
Pathway databases
- Reactome
Free, curated, peer-reviewed database of biological pathways, including signal transduction by growth factors and cytokines.
- KEGG Pathway
Pathway maps for signaling (MAPK, PI3K-Akt, JAK-STAT, Wnt and others) across species.
- STRING
Known and predicted protein-protein interaction networks.
Proteins, structures and pharmacology
- UniProt
Curated protein sequences and functions for ligands, receptors and signaling proteins.
- RCSB Protein Data Bank
3D structures of receptors, ligands and receptor-ligand complexes.
- IUPHAR/BPS Guide to Pharmacology
Expert-curated information on receptors, their ligands and drugs that target them.
- The Human Protein Atlas
Where in human tissues and cells proteins such as growth factors and receptors are expressed.
Literature and textbooks
- PubMed
Free index of biomedical literature; search terms such as "autocrine loop" or a specific ligand-receptor pair.
- NCBI Bookshelf
Free access to cell biology and molecular biology textbooks and reference works.
On this site
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